[PDF][PDF] Gastric stem cell research and gastric organoids

H Jeong, KT Nam - Organoid, 2022 - pdfs.semanticscholar.org
… initially identified as a stem cell marker along with Lgr5 [… cellular origin of gastric stem cells
in the corpus remains a matter of debate, researchers are trying to identify a molecular marker

The composition and roles of gastric stem cells in epithelial homeostasis, regeneration, and tumorigenesis

M Liu, Q Liu, Q Zou, J Li, Z Chu, J Xiang, WQ Chen… - Cellular Oncology, 2023 - Springer
markers of gastric stem/progenitor cells in the corpus and … tumor resident LGR5 + stem cells
emerge early in gastric cancer … gastric stem cell markers are enriched in LGR5–GFP + cells

Generation of a stem cell driven in vitro culture of polarized cells to study gastric tissue homeostasis and response to infections

S Wölffling - 2020 - edoc.hu-berlin.de
… in all the seminars and clubs but also during daily lab life and for … , Lgr5 was found to be the
specific marker for intestinal stem … it expresses Lgr5 and/or Axin2), in the corpus two stem cell

[PDF][PDF] Defining the identity and dynamics of adult gastric isthmus stem cells

S Han, J Fink, DJ Jörg, E Lee, MK Yum, L Chatzeli… - Cell stem cell, 2019 - cell.com
… the gastrointestinal tract and is rapidly turned over. Several markers have been proposed for
gastric corpus stem cells … The gland base is maintained by Troy+ or Lgr5+ (chief) stem cells, …

[PDF][PDF] Defining the identity and dynamics of adult gastric isthmus stem cells

L Mort10, O Basak11, H Clevers11, DE Stange… - core.ac.uk
… of the GI tract, the corpus epithelium hosts a stem cell population in the gland base, marked
by canonical, Wnt-responsive, stem cell markers such as Troy and Lgr5. However, these …

Proliferation and differentiation of gastric mucous neck and chief cells during homeostasis and injury-induced metaplasia

J Burclaff, SG Willet, JB Sáenz, JC Mills - Gastroenterology, 2020 - Elsevier
… base are believed to arise from descending mucous neck cells, which arise from stem cells.
… mammalian stomach corpus are poorly defined, largely due to lack of specific markers and …

[HTML][HTML] SLC26A9 deficiency causes gastric intraepithelial neoplasia in mice and aggressive gastric cancer in humans

X Liu, T Li, Z Ma, B Riederer, D Yuan, J Zhu, Y Li, J An… - Cellular Oncology, 2022 - Springer
… protein in both cell types [21]. Lgr5, which functions as a stem cell marker of chief cell
differentiation, … chief cells at the base of the corpus gland [22, 23]. Mist1 is expressed in both chief …

Parietal cell-Specific SLC26A9 Deletion induces spontaneous Gastric Carcinogenesis in Mice

X Liu, T Li, D Yuan, B Riederer, Z Ma, J Zhu, Y Li, J An… - bioRxiv, 2020 - biorxiv.org
Lgr5, which functions as a stem cell marker of chief cell … -proliferative zymogenic chief cells
at the base of corpus gland [21, … Lgr5 joins the club of gastric stem cell markers in the corpus. …

[HTML][HTML] Targeting Wnt signaling for the treatment of gastric cancer

S Koushyar, AG Powell, E Vincan… - International Journal of …, 2020 - mdpi.com
… commonly used in experiments to investigate the cell of origin in the corpus [35]. Further, …
stem cell marker LGR5 was found to promote proliferation, invasion, and migration of GC cells

[HTML][HTML] Pentraxin-3 inhibits milky spots metastasis of gastric cancer by inhibiting M2 macrophage polarization

X Cui, T Qin, Z Zhao, G Yang, JGP Sanches… - Journal of …, 2021 - ncbi.nlm.nih.gov
… the GC stem cell marker (LGR5) and found that the upregulation of PTX3 in MFCs decreased
the expression of LGR5 in … Lgr5 joins the club of gastric stem cell markers in the corpus. Nat …